Uri Gophna's Lab

Research Interests:

horizontal gene transfer lateral gene transfer archaea glycosylation mating S-layer surface layer recombination halophilic archaea intein CRISPR-Cas cas6 modularity phage repeats Show 18 more

selfish genetic elements Bacteremia Bacteremic E. coli homing endonuclease homing cycle Startup time Phosphate concentration Microbial fuel cell Microbial communities Anodic-biofilm development gut microbiota gut microbiome fecal microbiota colon butyrate Septicemia Extra-intestinal pathogenic E. coli virus

Laboratory location

Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel Aviv University, 69978, Tel Aviv, Israel.
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Contacts:

Lab activity (last 6 years)

Journals

Journal name	Impact factor	# of publications
Current topics in microbiology and immunology	5.829	1
RNA biology	5.216	1
Genes	3.191	1
Nucleic acids research	11.561	1
Proceedings of the National Academy of Sciences of the United States of America	9.504	1
Inflammatory bowel diseases	4.347	2
Bioresource technology	5.807	1
Trends in microbiology	11.776	1
Environmental microbiology reports	2.885	3
PLoS pathogens	6.158	1
International journal of medical microbiology IJMM		3
The FEBS journal	4.530	1
Archives of microbiology	1.607	1
PloS one	2.766	4
Extremophiles life under extreme conditions		1
International journal of antimicrobial agents	4.253	1
Research in microbiology	2.372	2
Bioengineered	1.639	1
Frontiers in genetics	4.151	1
Current biology CB		1
Scientific reports	4.122	1
Bioscience of microbiota food and health		1
Biology direct	2.649	1
Genomics	2.910	1
Science New York NY		1
Microbes and environments	2.476	1
Environmental microbiology	4.974	1
Biochemical Society transactions	3.394	1
Microbial ecology	3.614	1
Molecular biology and evolution	10.217	2
Genome biology	13.214	1

Publications

Pandemic Bacteremic Escherichia Coli Strains Evolution and Emergence of Drug-Resistant Pathogens,
[Journal Article] Current topics in microbiology and immunology (IF: 5.829) (2018)
Yair Y, Gophna U
Repeat modularity as a beneficial property of multiple CRISPR-Cas systems,
[Journal Article] RNA biology (IF: 5.216) (2018)
Yair Y, Gophna U
Comparative Analysis of Surface Layer Glycoproteins and Genes Involved in Protein Glycosylation in the Genus Haloferax,
[Journal Article] Genes (IF: 3.191) (2018)
Shalev Y, Soucy SM, Papke RT, Gogarten JP, Eichler J, Gophna U
High tolerance to self-targeting of the genome by the endogenous CRISPR-Cas system in an archaeon,
[Journal Article] Nucleic acids research (IF: 11.561) (2017)
Stachler AE, Turgeman-Grott I, Shtifman-Segal E, Allers T, Marchfelder A, Gophna U
Impact of a homing intein on recombination frequency and organismal fitness,
[Journal Article] Proceedings of the National Academy of Sciences of the United States of America (IF: 9.504) (2016)
Naor A, Altman-Price N, Soucy SM, Green AG, Mitiagin Y, Turgeman-Grott I, Davidovich N, Gogarten JP, Gophna U
Reply,
[Comment, Letter] Inflammatory bowel diseases (IF: 4.347) (2016)
Naftali T, Reshef L, Kovacs A, Porat R, Amir I, Konikoff FM, Gophna U
Community structure dynamics during startup in microbial fuel cells - The effect of phosphate concentrations,
[Journal Article] Bioresource technology (IF: 5.807) (2016)
Yanuka-Golub K, Reshef L, Rishpon J, Gophna U
Oscillospira a Central Enigmatic Component of the Human Gut Microbiota,
[Journal Article] Trends in microbiology (IF: 11.776) (2016)
Konikoff T, Gophna U
Distinct Microbiotas are Associated with Ileum-Restricted and Colon-Involving Crohns Disease,
[Journal Article] Inflammatory bowel diseases (IF: 4.347) (2016)
Naftali T, Reshef L, Kovacs A, Porat R, Amir I, Konikoff FM, Gophna U
Interactions between the intestinal microbiota and bile acids in gallstones patients,
[Journal Article] Environmental microbiology reports (IF: 2.885) (2015)
Keren N, Konikoff FM, Paitan Y, Gabay G, Reshef L, Naftali T, Gophna U
The gill microbiota of invasive and indigenous Spondylus oysters from the Mediterranean Sea and northern Red Sea,
[Journal Article] Environmental microbiology reports (IF: 2.885) (2015)
Roterman YR, Benayahu Y, Reshef L, Gophna U
Archaea in and on the Human Body Health Implications and Future Directions,
[Review] PLoS pathogens (IF: 6.158) (2015)
Lurie-Weinberger MN, Gophna U
Escherichia coli isolates from patients with bacteremic urinary tract infection are genetically distinct from those derived from sepsis following prostate transrectal biopsy,
[Journal Article] International journal of medical microbiology IJMM (2015)
Dan M, Yair Y, Samosav A, Gottesman T, Yossepowitch O, Harari-Schwartz O, Tsivian A, Schreiber R, Gophna U
Ribosomal mutations affecting the translation of genes that use non-optimal codons,
[Journal Article] The FEBS journal (IF: 4.530) (2014)
Pelchovich G, Nadejda S, Dana A, Tuller T, Bravo IG, Gophna U
Investigating a lotic microbial community following a severe detergent spill,
[Journal Article] Archives of microbiology (IF: 1.607) (2014)
Or A, Gophna U
Method for searching for homing endonucleases, their genes and their targets
[Patent #8566040] David E. Burstein, Adi Barzel, Eyal Privman, Uri Gophna, Martin Kupiec, Tal Pupko (2013)
Menaquinone and iron are essential for complex colony development in Bacillus subtilis,
[Journal Article] PloS one (IF: 2.766) (2013)
Pelchovich G, Omer-Bendori S, Gophna U
A halocin-H4 mutant Haloferax mediterranei strain retains the ability to inhibit growth of other halophilic archaea,
[Journal Article] Extremophiles life under extreme conditions (2013)
Naor A, Yair Y, Gophna U
The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics,
[Journal Article] International journal of medical microbiology IJMM (2013)
Pelchovich G, Schreiber R, Zhuravlev A, Gophna U
Effect of ribosome-targeting antibiotics on streptomycin-resistant Mycobacterium mutants in the rpsL gene,
[Journal Article] International journal of antimicrobial agents (IF: 4.253) (2013)
Pelchovich G, Zhuravlev A, Gophna U
In situ transplant analysis of free-living bacteria in a lotic ecosystem,
[Journal Article] Research in microbiology (IF: 2.372) (2013)
Or A, Comay O, Gophna U
Cell fusion and hybrids in Archaea prospects for genome shuffling and accelerated strain development for biotechnology,
[Journal Article] Bioengineered (IF: 1.639) (2013)
Naor A, Gophna U
Extensive Inter-Domain Lateral Gene Transfer in the Evolution of the Human Commensal Methanosphaera stadtmanae,
[Journal Article] Frontiers in genetics (IF: 4.151) (2012)
Lurie-Weinberger MN, Peeri M, Tuller T, Gophna U
A genetic investigation of the KEOPS complex in halophilic Archaea,
[Journal Article] PloS one (IF: 2.766) (2012)
Naor A, Thiaville PC, Altman-Price N, Cohen-Or I, Allers T, de Crcy-Lagard V, Gophna U
Low species barriers in halophilic archaea and the formation of recombinant hybrids,
[Journal Article] Current biology CB (2012)
Naor A, Lapierre P, Mevarech M, Papke RT, Gophna U
Fine-scale temporal dynamics of a fragmented lotic microbial ecosystem,
[Journal Article] Scientific reports (IF: 4.122) (2012)
Or A, Shtrasler L, Gophna U
Can Colonoscopy Aspirates be a Substitute for Fecal Samples in Analyses of the Intestinal Microbiota,
[Journal Article] Bioscience of microbiota food and health (2012)
Keren N, Naftali T, Kovacs A, Konikoff FM, Gophna U
Contribution of lateral gene transfer to the gene repertoire of a gut-adapted methanogen,
[Journal Article] Genomics (IF: 2.910) (2012)
Lurie-Weinberger MN, Peeri M, Gophna U
CRISPR loci reveal networks of gene exchange in archaea,
[Journal Article] Biology direct (IF: 2.649) (2011)
Brodt A, Lurie-Weinberger MN, Gophna U
Sequence features of E coli mRNAs affect their degradation,
[Journal Article] PloS one (IF: 2.766) (2011)
Lenz G, Doron-Faigenboim A, Ron EZ, Tuller T, Gophna U
Microbiology The guts of dietary habits,
[Comment, Journal Article] Science New York NY (2011)
Gophna U
Detection of spatial and temporal influences on bacterial communities in an urban stream by automated ribosomal intergenic ribosomal spacer analysis,
[Journal Article] Microbes and environments (IF: 2.476) (2011)
Or A, Gophna U
Composition and dynamics of the gill microbiota of an invasive Indo-Pacific oyster in the eastern Mediterranean Sea,
[Journal Article] Environmental microbiology (IF: 4.974) (2011)
Zurel D, Benayahu Y, Or A, Kovacs A, Gophna U
In vivo characterization of the homing endonuclease within the polB gene in the halophilic archaeon Haloferax volcanii,
[Journal Article] PloS one (IF: 2.766) (2011)
Naor A, Lazary R, Barzel A, Papke RT, Gophna U
Homing endonucleases residing within inteins evolutionary puzzles awaiting genetic solutions,
[Review] Biochemical Society transactions (IF: 3.394) (2011)
Barzel A, Naor A, Privman E, Kupiec M, Gophna U
Genotype is a stronger determinant than sex of the mouse gut microbiota,
[Journal Article] Microbial ecology (IF: 3.614) (2011)
Kovacs A, Ben-Jacob N, Tayem H, Halperin E, Iraqi FA, Gophna U
Integration of a foreign gene into a native complex does not impair fitness in an experimental model of lateral gene transfer,
[Journal Article] Molecular biology and evolution (IF: 10.217) (2010)
Omer S, Kovacs A, Mazor Y, Gophna U
The origins of eukaryotic-like proteins in Legionella pneumophila,
[Journal Article] International journal of medical microbiology IJMM (2010)
Lurie-Weinberger MN, Gomez-Valero L, Merault N, Glckner G, Buchrieser C, Gophna U
A systematic assessment of automated ribosomal intergenic spacer analysis ARISA as a tool for estimating bacterial richness,
[Evaluation Studies, Journal Article] Research in microbiology (IF: 2.372) (2010)
Kovacs A, Yacoby K, Gophna U
The gut microbiota of toll-like receptor 2-deficient mice exhibits lineage-specific modifications,
[Journal Article] Environmental microbiology reports (IF: 2.885) (2009)
Albert EJ, Sommerfeld K, Gophna S, Marshall JS, Gophna U
Neutrality of foreign complex subunits in an experimental model of lateral gene transfer,
[Journal Article] Molecular biology and evolution (IF: 10.217) (2008)
Wellner A, Gophna U
Complexity connectivity and duplicability as barriers to lateral gene transfer,
[Journal Article] Genome biology (IF: 13.214) (2007)
Wellner A, Lurie MN, Gophna U

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