Mahmoud Huleihel's Lab

Research Interests:

ERE ERα HTLV-1 Tax TPA BRCA-1 spermatogonial cells|Colletotrichum coccodes (C. coccodes) Multivariate analysis Herpes viruses HSV-1 VCG PCA LDA Fungal detection FTIR-ATR Show 12 more

in vitro culture spermatogenesis prepubertal cancer patient boys male infertility chemotherapy Sp1 site PKC isoforms NF-κB site Jurkat cell line HTLV-1 LTR HIV-1 LTR Raman spectroscopy

Laboratory location

3 Faculty of Health Sciences, Ben-Gurion University of the Negev , Beer-Sheva, Israel .
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Contacts:

Lab activity (last 6 years)

Journals

Journal name	Impact factor	# of publications
Stem cells and development	3.315	1
Biochemical and biophysical research communications	2.559	1
Cell cycle Georgetown Tex		2
Mediators of inflammation	3.549	1
PloS one	2.766	1
Anticancer research	1.865	1
European cytokine network	1.720	4
Journal of interferon cytokine research the official journal of the International Society for Interferon and Cytokine Research		3
Asian journal of andrology	3.259	1
Antiviral research	4.307	1
The open virology journal		1
New biotechnology	3.733	1
Leukemia research	2.319	1
Biopolymers	1.990	2
Prostaglandins other lipid mediators		1
Endocrinology	3.961	1
American journal of reproductive immunology New York NY 1989		2
Biochimica et biophysica acta		1
Applied spectroscopy	1.642	1
Journal of biomedical optics	2.367	1
Developmental science	4.078	1
Journal of reproductive immunology	2.322	1
Journal of pharmaceutical and biomedical analysis	2.831	1
Developmental neuroscience	2.133	1
Methods in molecular biology Clifton NJ		1
Spectrochimica acta Part A Molecular and biomolecular spectroscopy		1
Synapse New York NY		1
Brain behavior and immunity	6.306	1
Journal of biochemical and biophysical methods		1
International journal of molecular medicine	2.784	1
Photochemistry and photobiology	2.214	1
Cardiovascular research	6.290	1
Cancer cell international	3.960	1

Publications

Development of Postmeiotic Cells In Vitro from Spermatogonial Cells of Prepubertal Cancer Patients,
[Journal Article] Stem cells and development (IF: 3.315) (2018)
Abofoul-Azab M, AbuMadighem A, Lunenfeld E, Kapelushnik J, Shi Q, Pinkas H, Huleihel M
Different molecular mechanisms of HTLV-1 and HIV LTR activation by TPA,
[Journal Article] Biochemical and biophysical research communications (IF: 2.559) (2018)
Jabareen A, Suleman M, Abu-Jaafar A, Huleihel M
Effect of TPA and HTLV-1 Tax on BRCA1 and ERE controlled genes expression,
[Journal Article] Cell cycle Georgetown Tex (2017)
Jabareen A, Abu-Jaafar A, Abou-Kandil A, Huleihel M
Differential effects of HTLV-1 Tax oncoprotein on the different estrogen-induced-ER -mediated transcriptional activities,
[Journal Article] Cell cycle Georgetown Tex (2016)
Abou-Kandil A, Eisa N, Jabareen A, Huleihel M
Expression of IL-18 IL-18 binding protein and IL-18 receptor by normal and cancerous human ovarian tissues possible implication of IL-18 in the pathogenesis of ovarian carcinoma,
[Journal Article] Mediators of inflammation (IF: 3.549) (2014)
Medina L, Rabinovich A, Piura B, Dyomin V, Levy RS, Huleihel M
HTLV-1 Tax oncoprotein inhibits the estrogen-induced-ER -Mediated BRCA1 expression by interaction with CBPp300 cofactors,
[Journal Article] PloS one (IF: 2.766) (2014)
Shukrun M, Jabareen A, Abou-Kandil A, Chamias R, Aboud M, Huleihel M
Distinct expression and localization of TNF system in ovarian carcinoma tissues possible involvement of TNF- in morphological changes of ovarian cancerous cells,
[Journal Article] Anticancer research (IF: 1.865) (2014)
Piura B, Medina L, Rabinovich A, Dyomin V, Levy RS, Huleihel M
Thalidomide distinctly affected TNF- IL-6 and MMP secretion by an ovarian cancer cell line SKOV-3 and primary ovarian cancer cells,
[Journal Article] European cytokine network (IF: 1.720) (2013)
Piura B, Medina L, Rabinovich A, Dyomin V, Huleihel M
Placental secretion of interleukin-1 and interleukin-1 receptor antagonist in preeclampsia effect of magnesium sulfate,
[Clinical Trial, Journal Article, Multicenter Study] Journal of interferon cytokine research the official journal of the International Society for Interferon and Cytokine Research (2012)
Amash A, Holcberg G, Sapir O, Huleihel M
Differentiation of murine male germ cells to spermatozoa in a soft agar culture system,
[Journal Article] Asian journal of andrology (IF: 3.259) (2012)
Abu Elhija M, Lunenfeld E, Schlatt S, Huleihel M
Effect of propolis and caffeic acid phenethyl ester CAPE on NFB activation by HTLV-1 Tax,
[Journal Article] Antiviral research (IF: 4.307) (2011)
Shvarzbeyn J, Huleihel M
Distinct expression of interleukin-1 interleukin-1 and interleukin-1 receptor antagonist in testicular tissues and cells from human biopsies with normal and abnormal histology,
[Journal Article] Journal of interferon cytokine research the official journal of the International Society for Interferon and Cytokine Research (2011)
Abu Elheija M, Dyomin V, Ganaiem M, Lunenfeld E, Vardy NS, Huleihel M
Magnesium sulfate normalizes placental interleukin-6 secretion in preeclampsia,
[Journal Article] Journal of interferon cytokine research the official journal of the International Society for Interferon and Cytokine Research (2010)
Amash A, Holcberg G, Sheiner E, Huleihel M
Anti-Herpetic Activity of Callissia fragrans and Simmondsia chinensis Leaf Extracts In Vitro,
[Journal Article] The open virology journal (2010)
Yarmolinsky L, Zaccai M, Ben-Shabat S, Huleihel M
Antiviral activity of ethanol extracts of Ficus binjamina and Lilium candidum in vitro,
[Journal Article] New biotechnology (IF: 3.733) (2009)
Yarmolinsky L, Zaccai M, Ben-Shabat S, Mills D, Huleihel M
Dominant negative Tax double mutants as molecular inhibitors for wt Tax gene functions,
[Journal Article] Leukemia research (IF: 2.319) (2009)
Egbaria M, Tabakin-Fix Y, Huleihel M
Spectroscopic detection and identification of infected cells with herpes viruses,
[Journal Article] Biopolymers (IF: 1.990) (2009)
Erukhimovitch V, Karpasasa M, Huleihel M
Lipopolysaccharide differently affects prostaglandin E2 levels in fetal and maternal compartments of perfused human term placenta,
[Journal Article] Prostaglandins other lipid mediators (2009)
Amash A, Holcberg G, Sheiner E, Fleisher-Berkovich S, Myatt L, Huleihel M
Effect of interleukin-1 receptor antagonist gene deletion on male mouse fertility,
[Journal Article] Endocrinology (IF: 3.961) (2009)
Ganaiem M, AbuElhija M, Lunenfeld E, Cherniy N, Weisze N, Itach SB, Breitbart H, Apte R, Huleihel M
Lipopolysaccharide increased the expression levels of IL-18 ICE and IL-18 R in murine Leydig cells,
[Journal Article] American journal of reproductive immunology New York NY 1989 (2008)
AbuElhija M, Lunenfeld E, Eldar-Geva T, Huleihel M
Monitoring of viral cancer progression using FTIR microscopy a comparative study of intact cells and tissues,
[Journal Article] Biochimica et biophysica acta (2008)
Bogomolny E, Argov S, Mordechai S, Huleihel M
Constitutive expression of IL-18 binding protein in murine testicular tissues and cells,
[Journal Article] European cytokine network (IF: 1.720) (2008)
Abu Elhija M, Lunenfeld E, Persky L, Huleihel M
Early and rapid detection of potatos fungal infection by Fourier transform infrared microscopy,
[Evaluation Studies, Journal Article] Applied spectroscopy (IF: 1.642) (2007)
Erukhimovitch V, Tsror Lahkim L, Hazanovsky M, Talyshinsky M, Souprun Y, Huleihel M
Use of Fourier transform infrared microscopy for the evaluation of drug efficiency,
[Journal Article] Journal of biomedical optics (IF: 2.367) (2006)
Erukhimovitch V, Talyshinsky M, Souprun Y, Huleihel M
The effect of prenatal hypoxia on brain development short- and long-term consequences demonstrated in rodent models,
[Review] Developmental science (IF: 4.078) (2006)
Golan H, Huleihel M
Different effects of magnesium sulfate and angiotensin II on the capacity of the fetal and maternal compartments of normal human placenta to secrete TNF-alpha and IL-6,
[Journal Article] Journal of reproductive immunology (IF: 2.322) (2006)
Holcberg G, Amash A, Sapir O, Hallak M, Sheiner E, Ducler D, Katz M, Huleihel M
Testicular interleukin-6 response to systemic inflammation,
[Journal Article] European cytokine network (IF: 1.720) (2005)
Elhija MA, Potashnik H, Lunenfeld E, Potashnik G, Schlatt S, Nieschlag E, Huleihel M
Interleukin-6 expression during normal maturation of the mouse testis,
[Journal Article] European cytokine network (IF: 1.720) (2005)
Potashnik H, Elhija MA, Lunenfeld E, Potashnik G, Schlatt S, Nieschlag E, Huleihel M
FTIR microscopy as a method for identification of bacterial and fungal infections,
[Journal Article] Journal of pharmaceutical and biomedical analysis (IF: 2.831) (2005)
Erukhimovitch V, Pavlov V, Talyshinsky M, Souprun Y, Huleihel M
FTIR microscopy detection of cells infected with viruses,
[Journal Article] Methods in molecular biology Clifton NJ (2005)
Erukhimovitch V, Talyshinsky M, Souprun Y, Huleihel M
Maternal hypoxia during pregnancy delays the development of motor reflexes in newborn mice,
[Journal Article] Developmental neuroscience (IF: 2.133) (2004)
Golan H, Kashtutsky I, Hallak M, Sorokin Y, Huleihel M
The use of FTIR microscopy for evaluation of herpes viruses infection development kinetics,
[Journal Article] Spectrochimica acta Part A Molecular and biomolecular spectroscopy (2004)
Erukhimovitch V, Mukmanov I, Talyshinsky M, Souprun Y, Huleihel M
Selective vasodilator effect of magnesium sulfate in human placenta,
[Journal Article] American journal of reproductive immunology New York NY 1989 (2004)
Holcberg G, Sapir O, Hallak M, Alaa A, Shorok HY, David Y, Katz M, Huleihel M
Distinct expression and distribution of vesicular proteins in the hippocampus of TNFa-deficient mice during development,
[Journal Article] Synapse New York NY (2004)
Golan H, Levav T, Huleihel M
Psychological factors correlate meaningfully with percent-monocytes among acute coronary syndrome patients,
[Clinical Trial, Journal Article] Brain behavior and immunity (IF: 6.306) (2003)
Gidron Y, Armon T, Gilutz H, Huleihel M
FTIR microspectroscopy of malignant fibroblasts transformed by mouse sarcoma virus,
[Evaluation Studies, Journal Article] Journal of biochemical and biophysical methods (2003)
Salman A, Ramesh J, Erukhimovitch V, Talyshinsky M, Mordechai S, Huleihel M
Activation of HTLV-I long terminal repeat by apoptosis inducing agents mechanism and implications for HTLV-I pathogenicity review,
[Review] International journal of molecular medicine (IF: 2.784) (2003)
Schavinsky-Khrapunsky Y, Gold E, Ben-Aroya Z, Torgeman A, Aboud M, Huleihel M
Spectroscopic characterization of human and mouse primary cells cell lines and malignant cells,
[Journal Article] Photochemistry and photobiology (IF: 2.214) (2002)
Erukhimovitch V, Talyshinsky M, Souprun Y, Huleihel M
Molecular and cellular interface between behavior and acute coronary syndromes,
[Review] Cardiovascular research (IF: 6.290) (2002)
Gidron Y, Gilutz H, Berger R, Huleihel M
FTIR spectroscopic method for detection of cells infected with herpes viruses,
[Journal Article] Biopolymers (IF: 1.990) (2002)
Salman A, Erukhimovitch V, Talyshinsky M, Huleihil M, Huleihel M
Anti-viral activity of red microalgal polysaccharides against retroviruses,
[Journal Article] Cancer cell international (IF: 3.960) (2002)
Talyshinsky MM, Souprun YY, Huleihel MM

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